Figure 3.

Schematic biosynthesis of the HBGA ABH and Lewis. Several transferase enzymes (boxed) are involved in the addition of relevant monosaccharides (in bold) to synthesise the ABH and Lewis ligands in a variety of tissues. Gal, Galactose; Glc, Glucose; GalNAc, N-Acetylgalactosamine; GlcNAc, N-Acetylglucosamine; Fuc, Fucose. With kind permission from Springer Science + Business Media: Glycoconjugate journal, Norwalk virus-like particles bind specifically to A, H and difucosylated Lewis but not to B histo-blood group active glycosphingolipids, 26(9), 2009, 1172, Nilsson J, Rydell GE, Le Pendu J, Larson G, Figure 1 (the figure includes minor alterations).

Abrantes et al. Veterinary Research 2012 43:12   doi:10.1186/1297-9716-43-12
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