Measured ODn values plotted against infection dose. Immunological response on day 7 (open circle), day 14 (open diamond), day 21 (black circle), day 28 (black square), day 35 (black diamond) and day 42 (black triangle) pi. Infection doses 200 and 400 ML of both low and high dose experiments are displayed. A. Average ODn ± SE values show a positive correlation with infection, both in time and infection dose, although less pronounced at low infection doses (10-400 ML). At the highest doses (12 000-14 000 ML), ODn values decline between day 14 and day 42 pi as compared to the 10 000 ML infection group. Intermediate time points are not shown for the sake of clarity. B. Average ODn values of infection groups 2 000-10 000 ML correlate significantly (P < 0.05) with infection dose on all time points C. Average ODn values of infection groups 10-400 ML correlate significantly (P < 0.05) with infection dose on all time points, except 7 dpi.
Franssen et al. Veterinary Research 2011 42:113 doi:10.1186/1297-9716-42-113